Background:

Histones play a critical role in transcriptional regulation| cell cycle progression| and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Classification:

Primary antibody

Alternative names:

Histone deacetylase 6; HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human HDAC6 around the phosphorylation site of Ser22. AA range:7-56

Concentration:

1 mg/ml

Molecular weight:

131431

Applications:

WB, IHC-p, IF, ICC, ELISA

Storage:

-20°C for 1 year

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