Background:

This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism| the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also| this protein contains a peptide that has antimicrobial activity against E. coli| P. aeruginosa| and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins| the regulation of mRNA stability| and acting as a transferri

Classification:

Primary antibody

Alternative names:

Glyceraldehyde-3-phosphate dehydrogenase; GAPDH; GAPD; CDABP0047; OK/SW-cl.12; Glyceraldehyde-3-phosphate dehydrogenase; GAPDH; Peptidyl-cysteine S-nitrosylase GAPDH

Species reactivity:

Human, Mouse, Rat, Rabbit, Chicken, Monkey, Sheep

Host:

Rabbit

Isotype:

IgG

Immunogen:

Recombinant Protein of GAPDH

Concentration:

Molecular weight:

Applications:

WB, IHC-p, IF

Storage:

-20°C for 1 year

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