Background:

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts| hypogammaglobulinemia| infections| and myelokathexis) syndrome. Alternate transcriptional splice variants| encoding different isoforms| have been characterized.

Classification:

Primary antibody

Alternative names:

C-X-C chemokine receptor type 4; CXCR4; C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; FB22; Fusin; HM89; LCR1; Leukocyte-derived seven transmembrane domain receptor; LESTR; NPYRL; Stromal cell-derived factor 1 receptor; SDF-1 receptor; CD antigen CD184

Species reactivity:

Human, Mouse, Rat, Monkey

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human CXCR4 around the phosphorylation site of Ser339. AA range:303-352

Concentration:

1 mg/ml

Molecular weight:

39746

Applications:

WB, IHC-p, IF, ICC, ELISA

Storage:

-20°C for 1 year

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