Background:

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules| including a propeptide region| a metalloproteinase domain| a disintegrin-like domain| and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs| and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain| and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia.

Classification:

Primary antibody

Alternative names:

ATL2; ADAMTS-like protein 2; ADAMTSL-2

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human ATL2

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB

Storage:

-20°C for 1 year

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