Background:

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family| this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion| migration and organization| and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Classification:

Primary antibody

Alternative names:

Ezrin; EZR; VIL2; Ezrin; Cytovillin; Villin-2; p81

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Ezrin around the phosphorylation site of Thr566. AA range:534-583

Concentration:

1 mg/ml

Molecular weight:

69413

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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