Background:

This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus| cytoplasm| and mitochondria. Upon binding to 17beta-estradiol or related ligands| the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described| but the full-length nature of some of these variants has not been fully characterized.

Classification:

Primary antibody

Alternative names:

Estrogen receptor beta; ESR2; ESTRB; NR3A2; Estrogen receptor beta; ER-beta; Nuclear receptor subfamily 3 group A member 2

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Estrogen Receptor-beta around the phosphorylation site of Ser105. AA range:71-120

Concentration:

1 mg/ml

Molecular weight:

59216

Applications:

WB, IF, ICC, ELISA

Storage:

-20°C for 1 year

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