Background:

The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether| which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin| and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.

Classification:

Primary antibody

Alternative names:

ASPC1

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human ASPC1

Concentration:

1 mg/ml

Molecular weight:

60830

Applications:

WB

Storage:

-20°C for 1 year

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