Background:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases| also known as extracellular signal-regulated kinases (ERKs)| act in a signaling cascade that regulates various cellular processes such as proliferation| differentiation| and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases| resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

Classification:

Primary antibody

Alternative names:

Mitogen-activated protein kinase 3; MAPK3; ERK1; PRKM3; Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human p44/42 MAP Kinase around the phosphorylation site of Tyr204. AA range:170-219

Concentration:

1 mg/ml

Molecular weight:

43136

Applications:

WB, IHC-p, IF, ICC, ELISA

Storage:

-20°C for 1 year

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