Background:

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element| an octameric palindrome. The protein is phosphorylated by several protein kinases| and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.

Classification:

Primary antibody

Alternative names:

Cyclic AMP-responsive element-binding protein 1; CREB1; Cyclic AMP-responsive element-binding protein 1; CREB-1; cAMP-responsive element-binding protein 1

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human CREB around the phosphorylation site of Ser133. AA range:100-149

Concentration:

1 mg/ml

Molecular weight:

36688

Applications:

IF, ICC, WB, IHC-p, IP, ELISA

Storage:

-20°C for 1 year

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