Background:

This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome| suggesting that this gene functions in the differentiation of neural crest cell derivatives.

Classification:

Primary antibody

Alternative names:

AP2B

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human AP2B

Concentration:

1 mg/ml

Molecular weight:

50600

Applications:

WB

Storage:

-20°C for 1 year

More info:

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