Background:

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets| forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet| with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene| a member of the claudin family| is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin| and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

Classification:

Primary antibody

Alternative names:

Claudin-3; CLDN3; C7orf1; CPETR2; Claudin-3; Clostridium perfringens enterotoxin receptor 2; CPE-R 2; CPE-receptor 2; Rat ventral prostate.1 protein homolog; hRVP1

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Claudin 3 around the phosphorylation site of Tyr219. AA range:171-220

Concentration:

1 mg/ml

Molecular weight:

23319

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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