Background:

This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19.

Classification:

Primary antibody

Alternative names:

CEAM6; Carcinoembryonic antigen-related cell adhesion molecule 6; Non-specific crossreacting antigen; Normal cross-reacting antigen; CD antigen CD66c

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human CEAM6

Concentration:

1 mg/ml

Molecular weight:

Applications:

IHC-p, IF, WB

Storage:

-20°C for 1 year

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