Background:

This gene encodes a 42.3 kD subunit of dynactin| a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions| including ER-to-Golgi transport| the centripetal movement of lysosomes and endosomes| spindle formation| chromosome movement| nuclear positioning| and axonogenesis. This subunit| like ACTR1A| is an actin-related protein. These two proteins| which are of equal length and share 90% amino acid identity| are present in a constant ratio of approximately 1:15 in the dynactin complex.

Classification:

Primary antibody

Alternative names:

ACTY

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human ACTY

Concentration:

1 mg/ml

Molecular weight:

41360

Applications:

WB

Storage:

-20°C for 1 year

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