Background:

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA| the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I| the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation| rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms.

Classification:

Primary antibody

Alternative names:

ACACB

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human ACACB

Concentration:

1 mg/ml

Molecular weight:

270380

Applications:

WB

Storage:

-20°C for 1 year

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