Background:

This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold| plexin| transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis| inflammation| the immune response| and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas| including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Classification:

Primary antibody

Alternative names:

Proto-oncogene c-Rel; REL; Proto-oncogene c-Rel

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Rel around the phosphorylation site of Ser503. AA range:470-519

Concentration:

1 mg/ml

Molecular weight:

68520

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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