Background:

CTNNA1 encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. Catenin alpha-1 contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy.

Classification:

Primary antibody

Alternative names:

CTNNA1; Catenin alpha-1; Alpha E-catenin; Cadherin-associated protein; Renal carcinoma antigen NY-REN-13

Species reactivity:

Human;mouse;rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Catenin-alpha1 around the phosphorylation site of Ser641. AA range:607-656

Concentration:

1 mg/ml

Molecular weight:

100071

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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