Background:

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for YWHAZ.

Classification:

Primary antibody

Alternative names:

YWHAZ; 14-3-3 protein zeta/delta; Protein kinase C inhibitor protein 1; KCIP-1

Species reactivity:

Human;mouse;rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human 14-3-3 zeta around the phosphorylation site of Ser58. AA range:24-73

Concentration:

1 mg/ml

Molecular weight:

27745

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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