Background:

BMX (BMX non-receptor tyrosine kinase) encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for BMX.

Classification:

Primary antibody

Alternative names:

BMX; Cytoplasmic tyrosine-protein kinase BMX; Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; ETK; NTK38

Species reactivity:

Human;mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ETK around the phosphorylation site of Tyr566. AA range:532-581

Concentration:

1 mg/ml

Molecular weight:

78011

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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