Background:

BID (BH3 interacting domain death agonist) encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

Classification:

Primary antibody

Alternative names:

BID; BH3-interacting domain death agonist; p22 BID; BID

Species reactivity:

Human;mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human BID around the phosphorylation site of Ser78. AA range:44-93

Concentration:

1 mg/ml

Molecular weight:

21995

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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