Background:

XRCC3 encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.

Classification:

Primary antibody

Alternative names:

XRCC3; DNA repair protein XRCC3; X-ray repair cross-complementing protein 3

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human XRCC3. AA range:41-90

Concentration:

1 mg/ml

Molecular weight:

37850

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for one year

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