Background:

The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. WTAP encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, pre-mRNA-splicing regulator WTAP is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several transcript variants encoding three different isoforms.

Classification:

Primary antibody

Alternative names:

WTAP; KIAA0105; Pre-mRNA-splicing regulator WTAP; Female-lethal(2)D homolog; hFL(2)D; WT1-associated protein; Wilms tumor 1-associating protein

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human WTAP. AA range:321-370

Concentration:

1 mg/ml

Molecular weight:

44244

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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