Background:

TYK2 encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. Non-receptor tyrosine-protein kinase TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Classification:

Primary antibody

Alternative names:

TYK2; Non-receptor tyrosine-protein kinase TYK2

Species reactivity:

Human;Mouse;Monkey

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human TYK2. AA range:1020-1069

Concentration:

1 mg/ml

Molecular weight:

133650

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

More info:

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