Background:

Mutations in TSC2 (tuberous sclerosis 2) lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

Classification:

Primary antibody

Alternative names:

TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Tuberin. AA range:947-996

Concentration:

1 mg/ml

Molecular weight:

200749

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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