Background:

TCOF1 (treacle ribosome biogenesis factor 1) encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in TCOF1 have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for TCOF1.

Classification:

Primary antibody

Alternative names:

TCOF1; Treacle protein; Treacher Collins syndrome protein

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human TCOF1. AA range:41-90

Concentration:

1 mg/ml

Molecular weight:

152104

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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