Background:

Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at Thr-288 and protects this residue against dephosphorylation.

Classification:

Primary antibody

Alternative names:

TPX2; C20orf1; C20orf2; DIL2; IL 2; IL 2; HCA519; Targeting protein for Xklp2; Differentially expressed in cancerous and non-cancerous lung cells 2; DIL-2; Hepatocellular carcinoma-associated antigen 519; Protein

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human DIL-2. AA range:301-350

Concentration:

1 mg/ml

Molecular weight:

85653

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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