Background:

TOP3A(topoisomerase(DNA) III alpha) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Classification:

Primary antibody

Alternative names:

TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from Topo IIIα . at AA range: 350-430

Concentration:

1 mg/ml

Molecular weight:

112372

Applications:

WB, ELISA

Storage:

-20°C for one year

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