Background:

TOP1 (topoisomerase (DNA) I) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. TOP1 is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.

Classification:

Primary antibody

Alternative names:

TOP1; DNA topoisomerase 1; DNA topoisomerase I

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from the Internal region of human Topo I.

Concentration:

1 mg/ml

Molecular weight:

90726

Applications:

WB, ELISA

Storage:

-20°C for one year

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