Background:

TMPRSS3 encodes transmembrane protease serine 3 that belongs to the serine protease family. The transmembrane protease serine 3 contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. TMPRSS3 was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.

Classification:

Primary antibody

Alternative names:

TMPRSS3; ECHOS1; TADG12; Transmembrane protease serine 3; Serine protease TADG-12; Tumor-associated differentially-expressed gene 12 protein

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human TMPRSS3. AA range:405-454

Concentration:

1 mg/ml

Molecular weight:

49405

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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