Background:

Serine/threonine-protein kinase tousled-like 1 encoded by TLK1 is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

TLK1; KIAA0137; Serine/threonine-protein kinase tousled-like 1; PKU-beta; Tousled-like kinase 1

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human TLK1. AA range:730-779

Concentration:

1 mg/ml

Molecular weight:

86700

Applications:

IF, ELISA

Storage:

-20°C for one year

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