Background:

TIMP3 belongs to the TIMP gene family. Metalloproteinase inhibitor 3 encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.

Classification:

Primary antibody

Alternative names:

TIMP3; Metalloproteinase inhibitor 3; Protein MIG-5; Tissue inhibitor of metalloproteinases 3; TIMP-3

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human TIMP3. AA range:91-140

Concentration:

1 mg/ml

Molecular weight:

24145

Applications:

WB, ELISA

Storage:

-20°C for one year

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