Background:

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. Protein-glutamine gamma-glutamyltransferase 2 encoded by TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the protein-glutamine gamma-glutamyltransferase 2 is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

TGM2; Protein-glutamine gamma-glutamyltransferase 2; Tissue transglutaminase; Transglutaminase C; TG(C); TGC; TGase C; Transglutaminase H; TGase H; Transglutaminase-2; TGase-2

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Transglutaminase 2. AA range:1-50

Concentration:

1 mg/ml

Molecular weight:

77329

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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