Background:

The protein encoded by TCP1 (t-complex 1) is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of TCP1, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from TCP1 have been found.

Classification:

Primary antibody

Alternative names:

TCP1; CCT1; CCTA; T-complex protein 1 subunit alpha; TCP-1-alpha; CCT-alpha

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from the Internal region of human TCP-1 α.

Concentration:

1 mg/ml

Molecular weight:

60344

Applications:

WB, ELISA

Storage:

-20°C for one year

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