Background:

TBX3 (T-box 3) is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in TBX3 cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of TBX3 results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.

Classification:

Primary antibody

Alternative names:

TBX3; T-box transcription factor TBX3; T-box protein 3

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human TBX3. AA range:301-350

Concentration:

1 mg/ml

Molecular weight:

79389

Applications:

WB, ELISA

Storage:

-20°C for one year

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