Background:

Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. STON1 encodes one of two human homologs of the Drosophila melanogaster stoned B protein. Stonin-1 is related to components of the endocytic machinery and exhibits a modular structure consisting of an N-terminal proline-rich domain, a central region of homology specific to the human stoned B-like proteins, and a C-terminal region homologous to the mu subunits of adaptor protein (AP) complexes. Read-through transcription of this gene into the neighboring downstream gene, which encodes TFIIA-alpha/beta-like factor, generates a transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

STON1; SALF; SBLF; STN1; Stonin-1; Stoned B-like factor

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human STON1. AA range:686-735

Concentration:

1 mg/ml

Molecular weight:

83141

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

More info:

Email: info@sobekbio.com

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