Background:

HTR2A encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in HTR2A are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

HTR2A; HTR2; 5-hydroxytryptamine receptor 2A; 5-HT-2; 5-HT-2A; Serotonin receptor 2A

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human 5-HT-2A. AA range:422-471

Concentration:

1 mg/ml

Molecular weight:

52603

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for one year

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