Background:

SP3 (Sp3 transcription factor) belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for SP3, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.

Classification:

Primary antibody

Alternative names:

SP3; Transcription factor Sp3; SPR-2; SP4; Transcription factor Sp4; SPR-1

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human SP3/4. AA range:671-720

Concentration:

1 mg/ml

Molecular weight:

82025

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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