Background:

UBXN11 (UBX domain protein 11) encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of UBXN11 contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1. and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for UBXN11.

Classification:

Primary antibody

Alternative names:

UBXN11; SOC; UBXD5; PP2243; UBX domain-containing protein 11; Colorectal tumor-associated antigen COA-1; Socius; UBX domain-containing protein 5

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human UBXD5. AA range:131-180

Concentration:

1 mg/ml

Molecular weight:

57373

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

More info:

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