Background:

SEMA3A is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. Semaphorin-3A can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.

Classification:

Primary antibody

Alternative names:

SEMA3A; SEMAD; Semaphorin-3A; Semaphorin III; Sema III

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human SEMA3A. AA range:688-737

Concentration:

1 mg/ml

Molecular weight:

88889

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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