Background:

The protein encoded by POLR1C (RNA polymerase I subunit C) is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in POLR1C have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

POLR1C; POLR1E; DNA-directed RNA polymerases I and III subunit RPAC1; DNA-directed RNA polymerase I subunit C; RNA polymerases I and III subunit AC1; AC40; DNA-directed RNA polymerases I and III 40 kD

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human POLR1C. AA range:101-150

Concentration:

1 mg/ml

Molecular weight:

39250

Applications:

WB, ELISA

Storage:

-20°C for one year

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