Background:

The protein encoded by ROBO2 (roundabout guidance receptor 2) belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in ROBO2 are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

ROBO2; KIAA1568; Roundabout homolog 2

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ROBO2. AA range:237-286

Concentration:

1 mg/ml

Molecular weight:

151200

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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