Background:

Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al. 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al. 2003 [PubMed 14508493]).

Classification:

Primary antibody

Alternative names:

DROSHA; RN3; RNASE3L; RNASEN; Ribonuclease 3; Protein Drosha; Ribonuclease III; RNase III; p241

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human RNase III Drosha. AA range:774-823

Concentration:

1 mg/ml

Molecular weight:

159316

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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