Background:

URI1 (URI1, prefoldin like chaperone) encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. URI1 may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for URI1, and a pseudogene of this gene is located on the long arm of chromosome 22.

Classification:

Primary antibody

Alternative names:

URI1; C19orf2; NNX3; PPP1R19; RMP; URI; Unconventional prefoldin RPB5 interactor 1; Protein NNX3; Protein phosphatase 1 regulatory subunit 19; RNA polymerase II subunit 5-mediating protein; RPB5-media

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human RMP. AA range:415-464

Concentration:

1 mg/ml

Molecular weight:

56764

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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