Background:

RFX2 (regulatory factor X2) is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by RFX2 is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for RFX2, and both variants utilize alternative polyadenylation sites.

Classification:

Primary antibody

Alternative names:

RFX2; DNA-binding protein RFX2; Regulatory factor X 2

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human RFX2. AA range:661-710

Concentration:

1 mg/ml

Molecular weight:

80003

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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