Background:

The protein encoded by RECK (reversion inducing cysteine rich protein with kazal motifs) is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for RECK.

Classification:

Primary antibody

Alternative names:

RECK; ST15; Reversion-inducing cysteine-rich protein with Kazal motifs; hRECK; Suppressor of tumorigenicity 15 protein

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human RECK. AA range:21-70

Concentration:

1 mg/ml

Molecular weight:

106457

Applications:

IHC-p, IF, WB, ELISA

Storage:

-20°C for one year

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