Background:

RASSF8 encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11. ;q13. ) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

RASSF8; C12orf2; Ras association domain-containing protein 8; Carcinoma-associated protein HOJ-1

Species reactivity:

Human;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from RASSF8 . at AA range: 60-140

Concentration:

1 mg/ml

Molecular weight:

48327

Applications:

WB, ELISA

Storage:

-20°C for one year

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