Background:

The advanced glycosylation end product (AGE) receptor encoded by AGER is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID: 18089847).

Classification:

Primary antibody

Alternative names:

AGER; RAGE; Advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human RAGE. AA range:133-182

Concentration:

1 mg/ml

Molecular weight:

42803/36193

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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