Background:

The protein encoded by RAD51B (RAD51 paralog B) is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of RAD51B was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.

Classification:

Primary antibody

Alternative names:

RAD51B; RAD51L1; REC2; DNA repair protein RAD51 homolog 2; R51H2; RAD51 homolog B; Rad51B; RAD51-like protein 1

Species reactivity:

Human;Mouse;Monkey

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human RAD51L1. AA range:201-250

Concentration:

1 mg/ml

Molecular weight:

42196

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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