Background:

A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.

Classification:

Primary antibody

Alternative names:

RAB11FIP2; KIAA0941; Rab11 family-interacting protein 2; Rab11-FIP2; NRip11

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human RAB11FIP2. AA range:340-389

Concentration:

1 mg/ml

Molecular weight:

58279

Applications:

WB, ELISA

Storage:

-20°C for one year

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