Background:

RAB3GAP1 encodes the catalytic subunit of a Rab GTPase activating protein. RAB3 GTPase activating protein catalytic subunit 1 forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. RAB3 GTPase activating protein catalytic subunit 1 mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in RAB3GAP1 are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

RAB3GAP1; KIAA0066; RAB3GAP; Rab3 GTPase-activating protein catalytic subunit; RAB3 GTPase-activating protein 130 kDa subunit; Rab3-GAP p130; Rab3-GAP

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human RAB3GAP1. AA range:538-587

Concentration:

1 mg/ml

Molecular weight:

110524

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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