Background:

The pleckstrin homology and RhoGEF domain containing G4 encoded by PLEKHG4 can function as a guanine nucleotide exchange factor (GEF) and may play a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Polymorphisms in the region of this gene have been found to be associated with spinocerebellar ataxia in some study populations. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

PLEKHG4; PRTPHN1; Puratrophin-1; Pleckstrin homology domain-containing family G member 4; PH domain-containing family G member 4; Purkinje cell atrophy-associated protein 1

Species reactivity:

Human;Monkey

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human PLEKHG4. AA range:654-703

Concentration:

1 mg/ml

Molecular weight:

130803

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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